When it comes to venomous snakes in South Carolina, there are six distinct species you should be aware of. These include the Copperhead, Cottonmouth (Water Moccasin), Eastern Diamondback Rattlesnake, Timber Rattlesnake, Pygmy Rattlesnake, and the Eastern Coral Snake. While all are present in the state, your likelihood of encountering them varies significantly by region and habitat.
Your goal should not be fear, but informed awareness. Understanding the key identification features and typical behaviors of these six snakes is the most effective way to ensure safe coexistence with South Carolina's native wildlife.

The "Pit Vipers": Understanding the Majority
Five of South Carolina's six venomous snakes belong to a group called pit vipers. They are identified by a heat-sensing "pit" between their eye and nostril, vertically elliptical (cat-like) pupils, and a distinctly triangular or spade-shaped head.
The Copperhead (Agkistrodon contortrix)
This is the most common venomous snake in the state and is responsible for the majority of snakebites.
Their distinctive pattern of dark, hourglass-shaped crossbands on a lighter brown or tan body makes them identifiable. Copperheads rely on camouflage and will often freeze when approached, which is why many accidental encounters occur.
The Cottonmouth / Water Moccasin (Agkistrodon piscivorus)
As its name implies, this heavy-bodied snake is almost always found in or near water sources like swamps, rivers, and lakes.
Adults are often dark brown or black, obscuring their patterns. When threatened, a Cottonmouth will frequently gape its mouth open, exposing the bright white interior that gives it its name.
The Eastern Diamondback Rattlesnake (Crotalus adamanteus)
This is the largest venomous snake in North America, known for its large size, distinct diamond-shaped markings, and the loud, unmistakable rattle at the end of its tail.
They prefer the dry, sandy habitats of the coastal plain, such as pine flatwoods and sandhills. A bite from this snake is a serious medical emergency.
The Timber / Canebrake Rattlesnake (Crotalus horridus)
The Timber Rattlesnake is a large, heavy-bodied snake found in forested, rugged terrain in the mountains and piedmont. The coastal plain variant is often called a "Canebrake" rattlesnake.
It is typically identified by dark, V-shaped crossbands over a gray, yellow, or pinkish-tan body and a solid black tail.
The Pygmy Rattlesnake (Sistrurus miliarius)
This is a very small snake, rarely exceeding two feet in length. Its tiny rattle is often difficult to hear, sounding more like the buzz of an insect than a classic rattle.
Look for a grayish body with dark blotches and often a reddish-brown stripe running down its back. They are found statewide in various habitats, typically near water sources.
The Elapid: A Different Kind of Venom
South Carolina is also home to one species from the elapid family, which is related to cobras and mambas. Elapids have fixed fangs and a potent neurotoxic venom that affects the nervous system.
The Eastern Coral Snake (Micrurus fulvius)
This is a brightly colored and slender snake with rings of red, yellow, and black that encircle its entire body. It has a blunt, black snout.
It is a secretive, reclusive snake that is rarely seen. The key to identification is the color pattern, remembered by the rhyme: "Red touches yellow, kill a fellow. Red touches black, friend of Jack."
Understanding the Real Risk
It's crucial to place the presence of these snakes in the proper context. They are a vital part of the ecosystem and want nothing to do with humans.
Behavior is Defensive, Not Aggressive
Snakes do not hunt or chase people. A bite is a last-resort defensive measure used when the snake feels trapped and threatened.
Camouflage is the Main Hazard
The highest risk of a bite comes not from aggressive snakes, but from accidentally surprising a well-camouflaged one. This is particularly true for Copperheads in leaf litter or pine straw.
Respect Their Space
The overwhelming majority of bites occur when people intentionally try to handle, harass, or kill a snake. Leaving them alone is the single most effective safety policy.
How to Stay Safe in Snake Country
Your actions and awareness are the best tools for preventing negative encounters.
- If you are hiking or walking in natural areas: Watch where you step, wear sturdy, closed-toe shoes, and never put your hands or feet into places you cannot see.
- If you are working in your yard: Wear gloves when handling brush or reaching into shrubs, be cautious when moving firewood or debris, and keep grass trimmed low.
- If you encounter a snake: Stop, slowly back away, and give it plenty of room to leave the area. Do not attempt to identify it up close.
By understanding their identities and behaviors, you can safely appreciate South Carolina's wildlife from a respectful distance.
Summary Table:
| Venomous Snake | Key Identifying Features | Typical Habitat |
|---|---|---|
| Copperhead | Hourglass-shaped crossbands, tan/brown body | Woodlands, leaf litter, suburban areas |
| Cottonmouth | Dark brown/black, white mouth lining when threatened | Swamps, rivers, lakes |
| Eastern Diamondback Rattlesnake | Large size, diamond-shaped markings, rattle | Coastal plains, sandy areas |
| Timber Rattlesnake | V-shaped crossbands, black tail, rattle | Forests, mountains, piedmont |
| Pygmy Rattlesnake | Small size, gray with dark blotches, faint rattle | Near water sources statewide |
| Eastern Coral Snake | Red, yellow, and black rings; "red touches yellow" | Secretive, sandy soils, wooded areas |
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